Honest drug prices & Medicare plan facts. Straight from federal data.
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Omeprazole (generic Prilosec): what pharmacies actually pay

Prices below are the National Average Drug Acquisition Cost (NADAC) — the federal government's weekly survey of what pharmacies actually pay their wholesalers, as of 07/22/2026. Your pharmacy's cash price includes their markup and dispensing cost, so it will be higher — but if it's many times this number, that's a signal to shop around.

Form & strengthPharmacy costUnitType
OMEPRAZOLE DR 10 MG CAPSULE$0.08per tablet/unitGeneric
OMEPRAZOLE DR 20 MG CAPSULE$0.03per tablet/unitGeneric
OMEPRAZOLE DR 20 MG ODT$0.43per tablet/unitOTC
OMEPRAZOLE DR 20 MG TABLET$0.39per tablet/unitOTC
OMEPRAZOLE DR 40 MG CAPSULE$0.05per tablet/unitGeneric
OMEPRAZOLE MAG DR 20 MG CAP$0.40per tablet/unitOTC
OMEPRAZOLE MAG DR 20 MG TABLET$0.43per tablet/unitOTC
OMEPRAZOLE MAG DR 20.6 MG CAP$0.40per tablet/unitOTC

Rough math: a typical 30-day supply of one tablet/day equals 30× the per-unit cost.

This is pricing information, not medical advice. Talk to your doctor or pharmacist before changing any medication.

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