Honest drug prices & Medicare plan facts. Straight from federal data.
🌐 English Español
Advertisement

Estradiol: what pharmacies actually pay

Prices below are the National Average Drug Acquisition Cost (NADAC) — the federal government's weekly survey of what pharmacies actually pay their wholesalers, as of 07/22/2026. Your pharmacy's cash price includes their markup and dispensing cost, so it will be higher — but if it's many times this number, that's a signal to shop around.

Form & strengthPharmacy costUnitType
ESTRADIOL 0.01% CREAM$0.38per gramGeneric
ESTRADIOL 0.025 MG PATCH(1/WK)$11.34per tablet/unitGeneric
ESTRADIOL 0.025 MG PATCH(2/WK)$7.83per tablet/unitGeneric
ESTRADIOL 0.0375 MG PATCH(1/WK)$11.42per tablet/unitGeneric
ESTRADIOL 0.0375 MG PATCH(2/WK)$8.03per tablet/unitGeneric
ESTRADIOL 0.05 MG PATCH (1/WK)$10.63per tablet/unitGeneric
ESTRADIOL 0.05 MG PATCH (2/WK)$7.98per tablet/unitGeneric
ESTRADIOL 0.06 MG PATCH (1/WK)$12.29per tablet/unitGeneric
ESTRADIOL 0.06% 1.25G GEL PUMP$3.51per gramGeneric
ESTRADIOL 0.075 MG PATCH(1/WK)$12.15per tablet/unitGeneric
ESTRADIOL 0.075 MG PATCH(2/WK)$7.69per tablet/unitGeneric
ESTRADIOL 0.1 MG PATCH (1/WK)$12.54per tablet/unitGeneric
ESTRADIOL 0.1 MG PATCH (2/WK)$7.74per tablet/unitGeneric
ESTRADIOL 0.1% (0.25 MG) GEL PK$1.14per tablet/unitGeneric
ESTRADIOL 0.1% (0.5 MG) GEL PKT$1.25per tablet/unitGeneric
ESTRADIOL 0.1% (0.75 MG) GEL PK$1.02per tablet/unitGeneric
ESTRADIOL 0.1% (1 MG) GEL PKT$1.28per gramGeneric
ESTRADIOL 0.1% (1.25 MG) GEL PK$1.02per gramGeneric
ESTRADIOL 0.5 MG TABLET$0.06per tablet/unitGeneric
ESTRADIOL 1 MG TABLET$0.06per tablet/unitGeneric
ESTRADIOL 10 MCG VAGINAL INSRT$5.91per tablet/unitGeneric
ESTRADIOL 2 MG TABLET$0.08per tablet/unitGeneric
ESTRADIOL VALERATE 100 MG/5 ML$20.93per mLGeneric
ESTRADIOL VALERATE 200 MG/5 ML$34.84per mLGeneric
ESTRADIOL VALERATE 50 MG/5 ML$18.28per mLGeneric

Rough math: a typical 30-day supply of one tablet/day equals 30× the per-unit cost.

This is pricing information, not medical advice. Talk to your doctor or pharmacist before changing any medication.

Which Medicare plans cover this drug?

Pick your state and county to see every plan there, filtered to this drug — with the tier, prior-authorization status, and estimated copay.

Advertisement

Other drug prices