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Isotretinoin: what pharmacies actually pay

Prices below are the National Average Drug Acquisition Cost (NADAC) — the federal government's weekly survey of what pharmacies actually pay their wholesalers, as of 07/22/2026. Your pharmacy's cash price includes their markup and dispensing cost, so it will be higher — but if it's many times this number, that's a signal to shop around.

Form & strengthPharmacy costUnitType
ISOTRETINOIN 10 MG CAPSULE$1.65per tablet/unitGeneric
ISOTRETINOIN 20 MG CAPSULE$5.62per tablet/unitGeneric
ISOTRETINOIN 25 MG CAPSULE$10.77per tablet/unitGeneric
ISOTRETINOIN 30 MG CAPSULE$4.00per tablet/unitGeneric
ISOTRETINOIN 40 MG CAPSULE$5.71per tablet/unitGeneric

Rough math: a typical 30-day supply of one tablet/day equals 30× the per-unit cost.

This is pricing information, not medical advice. Talk to your doctor or pharmacist before changing any medication.

Which Medicare plans cover this drug?

Pick your state and county to see every plan there, filtered to this drug — with the tier, prior-authorization status, and estimated copay.

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