Methotrexate: what pharmacies actually pay
Prices below are the National Average Drug Acquisition Cost (NADAC) — the federal government's weekly survey of what pharmacies actually pay their wholesalers, as of 07/22/2026. Your pharmacy's cash price includes their markup and dispensing cost, so it will be higher — but if it's many times this number, that's a signal to shop around.
| Form & strength | Pharmacy cost | Unit | Type |
|---|---|---|---|
| METHOTREXATE 2.5 MG TABLET | $0.16 | per tablet/unit | Generic |
| METHOTREXATE 250 MG/10 ML VIAL | $1.98 | per mL | Generic |
| METHOTREXATE 50 MG/2 ML VIAL | $1.72 | per mL | Generic |
Rough math: a typical 30-day supply of one tablet/day equals 30× the per-unit cost.
This is pricing information, not medical advice. Talk to your doctor or pharmacist before changing any medication.
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